Ayano Inui Selected Research

4-phenylbutyric acid (Buphenyl)

11/2019	Effect of food on the pharmacokinetics and therapeutic efficacy of 4-phenylbutyrate in progressive familial intrahepatic cholestasis.
2/2016	Successful treatment with 4-phenylbutyrate in a patient with benign recurrent intrahepatic cholestasis type 2 refractory to biliary drainage and bilirubin absorption.
5/2014	Improved liver function and relieved pruritus after 4-phenylbutyrate therapy in a patient with progressive familial intrahepatic cholestasis type 2.
6/2010	Favorable effect of 4-phenylacetate on liver functions attributable to enhanced bile salt export pump expression in ornithine transcarbamylase-deficient children.

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Ayano Inui Research Topics

Disease

15	Infections 05/2022 - 06/2009
10	Fibrosis (Cirrhosis) 05/2022 - 05/2015
9	Hepatitis B 01/2022 - 01/2002
8	Liver Diseases (Liver Disease) 05/2022 - 05/2005
6	Liver Failure 01/2022 - 06/2002
6	Cholestasis 01/2021 - 06/2005
6	Hepatolenticular Degeneration (Wilson's Disease) 12/2019 - 06/2002
5	Adult-onset citrullinemia type 2 09/2021 - 04/2016
5	Chronic Hepatitis B 03/2021 - 11/2014
5	Hepatitis 03/2018 - 01/2002
4	Liver Cirrhosis (Hepatic Cirrhosis) 07/2022 - 11/2016
4	Intrahepatic Cholestasis 01/2021 - 02/2016
4	Acute Liver Failure (Fulminant Hepatic Failure) 10/2020 - 06/2002
4	Neonatal-onset citrullinemia type 2 01/2019 - 04/2016
4	Chronic Hepatitis C 04/2018 - 11/2009
3	Viremia 01/2022 - 04/2010
3	End Stage Liver Disease 01/2022 - 02/2014
3	Inflammation (Inflammations) 08/2021 - 11/2012
3	Abdominal Pain (Pain, Abdominal) 01/2021 - 08/2012
3	progressive familial intrahepatic 1 Cholestasis 01/2021 - 05/2014
3	Sclerosing Cholangitis 01/2021 - 01/2018
3	Autoimmune Hepatitis 04/2018 - 05/2005
2	Ulcerative Colitis 01/2021 - 01/2018
2	Citrullinemia 01/2021 - 01/2019
2	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 01/2021 - 12/2017
2	Hypergammaglobulinemia (Hyperimmunoglobulinemia) 05/2020 - 06/2005
2	Fever (Fevers) 05/2020 - 01/2017
2	Massive Hepatic Necrosis 03/2018 - 02/2010
2	Biliary Liver Cirrhosis (Primary Biliary Cirrhosis) 10/2017 - 02/2014
2	Hepatocellular Carcinoma (Hepatoma) 02/2017 - 11/2016
2	Pruritus (Itching) 02/2016 - 05/2014
2	Headache (Headaches) 07/2013 - 08/2004
2	Ornithine Carbamoyltransferase Deficiency Disease 07/2013 - 08/2004
2	Non-alcoholic Fatty Liver Disease 10/2012 - 11/2011
1	Hepatitis D 05/2022
1	Alcoholism (Alcohol Abuse) 05/2022
1	Hemorrhage 05/2022
1	Bacterial Infections (Bacterial Infection) 05/2022
1	Acute-On-Chronic Liver Failure 05/2022
1	Neoplasms (Cancer) 01/2022
1	Cholangitis 01/2021
1	Glycogen Storage Disease Type IV (Andersen's Disease) 09/2020
1	Multi-centric Castleman's Disease 05/2020
1	Lymphadenopathy 05/2020

Drug/Important Bio-Agent (IBA)

6	DNA (Deoxyribonucleic Acid)IBA 05/2022 - 01/2002
6	Alanine Transaminase (SGPT)IBA 01/2022 - 03/2006
5	CopperIBA 12/2019 - 06/2002
5	Hepatitis B e AntigensIBA 02/2017 - 11/2014
5	Immunoglobulins (Immunoglobulin)IBA 01/2016 - 01/2002
4	BilirubinIBA 05/2022 - 02/2016
4	Proteins (Proteins, Gene)FDA Link 09/2021 - 01/2019
4	EnzymesIBA 03/2021 - 06/2005
4	Antiviral Agents (Antivirals)IBA 03/2021 - 04/2015
4	citrinIBA 01/2021 - 01/2018
4	Transaminases (Aminotransferases)IBA 05/2020 - 11/2011
4	VaccinesIBA 11/2019 - 12/2006
4	4-phenylbutyric acid (Buphenyl)FDA Link 11/2019 - 06/2010
4	Urea (Carbamide)FDA LinkGeneric 01/2019 - 08/2004
4	Hepatitis B Vaccines (Hepatitis B Vaccine)IBA 02/2017 - 01/2002
3	Hepatitis B Surface Antigens (HBsAg)FDA Link 05/2022 - 04/2010
3	Cytidine Triphosphate (CTP)IBA 01/2022 - 02/2014
3	CarbohydratesIBA 09/2021 - 01/2019
3	Biomarkers (Surrogate Marker)IBA 08/2021 - 01/2018
3	Pharmaceutical PreparationsIBA 01/2021 - 02/2017
3	InterferonsIBA 03/2014 - 05/2011
2	Immunoglobulin G (IgG)IBA 03/2021 - 04/2018
2	Ursodeoxycholic Acid (Urso)FDA LinkGeneric 01/2021 - 01/2019
2	C-Reactive ProteinIBA 01/2021 - 05/2020
2	Member 11 Subfamily B ATP Binding Cassette TransporterIBA 06/2020 - 02/2016
2	Complement Membrane Attack Complex (Membrane Attack Complex)IBA 05/2019 - 05/2015
2	CholesterolIBA 01/2019 - 01/2018
2	LipidsIBA 01/2019 - 01/2018
2	ZincIBA 01/2018 - 12/2010
2	Immunoglobulin M (IgM)IBA 05/2017 - 01/2006
2	Anti-Bacterial Agents (Antibiotics)IBA 01/2017 - 05/2014
2	HLA Antigens (Human Leukocyte Antigens)IBA 11/2014 - 10/2007
2	Capsules (Microcapsules)IBA 10/2014 - 12/2013
2	Oxidants (Oxidizing Agents)IBA 11/2012 - 10/2006
2	AntioxidantsIBA 11/2012 - 10/2006
2	AntibodiesIBA 05/2005 - 01/2002
1	Guanosine Triphosphate (GTP)IBA 07/2022
1	gamma-Glutamyltransferase (gamma-Glutamyl Transpeptidase)IBA 07/2022
1	AntigensIBA 05/2022
1	Sphingosine-1-Phosphate ReceptorsIBA 01/2022
1	LipopolysaccharidesIBA 01/2022
1	sphingosine 1-phosphate (sphingosine-1-phosphate)IBA 01/2022
1	JTE 013IBA 01/2022
1	S100 Calcium-Binding Protein A4IBA 08/2021
1	ProteomeIBA 08/2021
1	Phospholipids (Phosphatides)FDA LinkGeneric 01/2021
1	Adenosine Triphosphatases (ATPase)IBA 01/2021
1	GlycogenIBA 09/2020
1	AmylopectinIBA 09/2020
1	Aspartate Aminotransferases (Aspartate Transaminase)IBA 05/2020
1	tocilizumab (atlizumab)FDA Link 05/2020

Therapy/Procedure

9	Liver Transplantation 01/2022 - 06/2002
6	Therapeutics 12/2015 - 03/2006
3	Drug Therapy (Chemotherapy) 03/2021 - 02/2010
2	Ligation 01/2022 - 08/2021
2	Fontan Procedure (Fontan Operation) 08/2021 - 07/2019